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Regeneron STS 2022 Application Now Open! The Regeneron STS 2022 application is now open! U.S. High School Seniors in the Class of 2022 are invited to apply online to the nation’s oldest and most prestigious STEM research competition. The Nation’s Oldest and Most Prestigious Science and Mathematics Competition Started in 1942 as the Westinghouse Science Talent Search, the Regeneron Science Talent Search (Regeneron STS) recognizes and empowers our nation’s most promising young scientists who are developing ideas that could solve society’s most urgent challenges. Each year, nearly 1,900 students enter the Regeneron STS, submitting original research in critically important scientific fields of study. Unique among high school competitions, the Regeneron STS focuses on identifying, inspiring, and engaging the most promising scientists among the nation’s high school seniors.